Typhoons Vicente (1208) and Kalmaegi (1415) were successfully simulated by the mesoscale weather research and forecasting (WRF) model using the NCEP (National Centers for Environmental Prediction) final operational global analysis data with the resolution of 1°×1°. The results showed that the simulated track and intensity of the typhoons are in consistence with Japan Meteorological Agency (JMA) best track data. The simulated surface wind nearly coincides with the station observation. Sensitivity experiments were then carried out to test the impact of terrain and land surface characteristics in Hong Kong and Shenzhen on the wind in Shenzhen area. Based on the sensitivity tests, we found that the wind influence on the Midwest Shenzhen induced by typhoons landing in western Guangdong is weakened by the terr-ain of Hong Kong. Hong Kong plays a role of slowering winds and protecting the Midwest Shenzhen from typhoons moving westward. Furthermore, it is found that the wind intensity in Yantian international container terminal is enhanced by the channel effect of Wutong Mountain in Shenzhen.