Based on the data of meteorological observation, NCEP and satellite remote sensing, the wind field characteristics and heat island distribution of Nanjing Jiangbei New Region were analyzed by using the methods of statistical analysis, numerical simulation and surface temperature retrieval. The ventilated corridor system of core area would be built with combinations of the land use status and new construction plan. The results indicate that the dominant wind direction is easterly, mountainvalley wind and landriver wind existing in local field. The wind speed is mainly concentrated in the period of 2-4 m·s-1, presenting downward trend in the recent 10 years. The wind speed in town and industrial park is small, for town and industrial park are stronger heat islands region. The fast wind speeds and freshair area are in the cool island area like Yangtze River, Laoshan and woodlands, where winds help air exchange with town. Combined with the local climate condition, topographic feature and landuse planning, we suggest the ventilated corridor system including 1 main ventilation corridor (northeastsouthwest), 3 minor ventilation corridors (northeastsouthwest) and 8 local ventilation corridors (southeastnorthwest, eastwest) could be built. In addition, the control index and construction strategy to the design length, width and layout of ventilated corridor were proposed.