Based on the fog observation data during 24-27 December 2006 (advection radiation fog), NCEP NC reanalysis data (2.5°×2.5°) and GDAS global meteorological data (1°×1°), detailed trajectory analysis of the boundary layer characteristics and water vapor transport of the fog is investigated, combined with the weather condition, meteorological elements and physical quantity field. The results show that: (1) there is thick inversion layer, even multi layer inversion throughout the dense fog event. Temperatures of different inversion tops in the middle and high levels are 2-5℃ higher than the surface temperature. The thickness of inversion layer is more than 200 m, and it gets to 500 m at 08:00 BT 26 December, indicating the atmosphere is very stable and conducive to the convergence of water vapor before the fog forms. However, it is not favorable for the divergence of water vapor after the formation of fog, which helps the development and maintenance of the fog, causing the fog to last about 64 hours with dense fog (visibility <50 m) about 37 hours; (2) The divergence of water vapor flux in low level is negative in the advection fog event. The upper air has persistent moisture convergence and the strongest moisture convergence appears at 02:00 BT 25 December, being -30×10-7 g·s-1·cm-2·hPa-1. The accumulation of low level water vapor makes fog form and develop while the divergence of water vapor flux speeds up its dissipation. 〖JP2〗The long lasting advection radiation fog is mainly caused by the continuous water vapor convergence; (3) The water vapor path is from the coastal area in easten China to Nanjing. The water vapor is continuously supplied from sea during the fog event, with the water vapor flux maximum getting to 2 g·s-1·hPa-1·cm-1. The sufficient supply and supplementary of water vapor determines the duration of the fog.