Based on the data of automatic observation stations, the characteristics of the air humidity, temperature and comfort index of urban microclimate zone, marine microclimate zone, mountain microclimate zone, hilly microclimate zone on typical clear days in Shenzhen were analyzed. And the results show that: the characteristics of the air humidity, temperature and comfort index of the four microclimate zones are obviously different. The minimum, maximum, average and diurnal variations of the air humidity, temperature and comfort index of the four microclimate zones are significantly different. In the daytime, the highest temperature occurs in the hilly microclimate zone, the second highest in the urban microclimate zone, and the lowest in the marine microclimate zone. In the nighttime, the lowest temperatures of the marine, urban, hilly and mountain microclimate zones rank from high to low in correct order. In the daytime, the hilly microclimate zone is the hottest, the urban microclimate zone is the second, and the marine microclimate zone is the most comfortable. While in the nighttime, the marine microclimate zone is the most uncomfortable, and the urban microclimate zone is the second, the mountain microclimate zone is the most comfortable.