According to the gas poisoning data provided by Prophylaxis and the Control Cent er of Hebei province and the meteorological data in winter from 2006 to 2007 yea r in Shijiazhuang, the relationship between carbon monoxide poisoning events and the meteorological condition was analyzed. The results indicated that:(1) the g as poisoning event mainly occurs in the night to the morning, specially in the coldest December and January; (2) Small wind velocity (grade 1 to 2), surface layer with inversion temperature gradient, small temperature change (within ±3 .0℃), fog and haze are the meteorological conditions favorable to the gas poiso ning; (3) 500 hPa upper air situations such as the west air current, westerly tr ough and upperlevel trough, and the ground synoptic situations such as weak high pressure, low pressure and equal pressure, are favorable to the poisoning event occurrence. In the forecast service these weather situat ions should be paid more consideration.