Taking PHOENICS as example, the principles of computational fluid dynamics (CFD) is described. The feasibility of applying the CFD method to numerical calculation of meteorological elements for street lane is discussed. A scheme for simulating and predicting meteorological fields in street lane is proposed, which is based on the nested CFD model into high-resolution numerical weather prediction model. A number of sensitivity analyses are run for the nesting problems at the boundary. It shows that nesting treatment is necessary and feasible in the calculation of meteorological fields. In addition, the effect of resolution on the results and duration of calculations is also discussed. In the final section, real cases are used to illustrate the application of the proposed scheme and the potential usefulness of the method.