The effects of the climatic changes on eco-environmental evolution are studied by using of the temperature and precipitation data at 4 typical stations from 1951 to 2004. The results show that (1)For the recent 54 year, the temperature rises notably in eastern region. The precipitation fluctuation is great and takes on a large increase trend, but the trend is not notable and in the range of climatic fluctuation. The precipitation is decreases since 1998 and has periodicity change of 11-year and 22-year. (2) Either the temperature or the precipitation is in high climatic essential state and climatic variability period at present, so the extreme climatic events increase. The climate becomes dry and warm, and its variability increases to intensify the extent of drought damage in eastern Inner Mongolia. Therefore, a series of eco-environmental problems is caused. For example, the area of the wetland will reduce, the grassland will degenerate and so on. (3) The results from the satellite remote data of the demonstration region reveal that the increase of stationary sands area illustrates the whole Horqin Sands improves benignly in the ecological aspect. But the increase of all kinds of sands class shows that the extent of cracked sands intensifies and local desert worsens in the present climatic condition.